This is the mindset at colleges and universities. "If you’re doing shit like eat ing Takis with Red 40 every day, you can’t throw a stone in a glass house.” Marie has sim ilar feel ings. On the social net work Fizz, girls at her college talk about getting skinny in one of two ways: Ozempic or cocaine. “I’d rather be on Ozempic,” she says.
GLP-1s reduce body weight by 5–18 % in trials, with modestly lower effects in real-world analyses, with multiple demonstrated clinical benefits. Challenges include side effects, especially gastrointestinal; nutritional deficiencies due to calorie reduction; muscle and bone loss; low long-term adherence with subsequent weight regain; and high costs with resulting low cost-effectiveness.
Contrave contains a combination of bupropion and naltrexone. Bupropion is an antidepressant medicine that can also decrease appetite. Naltrexone is usually given to block the effects of opioids or alcohol in people with addiction problems. Naltrexone may also curb hunger and food cravings.
Part addiction self-portrait, part medical exposé, Benjamin Flaherty’s powerful, essayistic “Shuffle” was the winner of this year’s Documentary Feature Competition at SXSW.
